In all such cases, the current formulation is straightforward to make use of, being in foam state when applied and becoming liquid upon rubbing onto the skin.
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The invention relates to an alcohol-free cosmetic or pharmaceutical foam composition comprising water, a hydrophobic solvent, a surface-active agent, a gelling agent, an lively component selected from the group of urea, hydroxy acid and a therapeutic enhancer and a propellant. The pharmaceutical provider in line with the present invention may also be used to prepare cosmetics for beauty goal by including into skincare agents and fragrance. The composition may embrace lively brokers for the treatment of psoriasis. 24. The foamable composition of claim 1, further comprising a gelling agent.
The penetration of the lively agent is enhanced due to the urea present within the foam composition. In a further class of froth adjuvants, the carbon chain of the fatty acid is substituted with a hydroxyl group, resembling 12-hydroxy stearic acid. 25. The foamable composition of declare 24, wherein the carrier additional contains a therapeutically effective amount of at the least one energetic agent.
The focus of the fatty alcohol, required to help the froth system is inversely associated to the size of its carbon chains. Fifty years ago, or as just lately as 10 and even 5, one skin-care product could final you a couple of weeks or typically months.
In a number of embodiments of the present invention, the hydrophobic solvent is included within the foamable composition at a concentration of 5% to about 10% (Class A), or 10% to about 20% (Class B), or about 20% to about 50% (Class C). The floor-active agent focus is about 0.1% to about 5%; the focus of the gelling agent is zero.01% to about 5% by weight and the liquefied gas propellant is included at a concentration of about 3% to about 18% of the total composition.
Wu et al., Interplay of Fatty Acid Monolayers with Cobalt Nanoparticles,†Nano Letters, 2004, 4(2): 383-386. The hydrophobic solvent present in the foam composition helps retain the insect repellent on the skin floor for an prolonged time period. Urea additional possesses skin exfoliating properties, which are helpful in the management of passage of energetic brokers by means of the dermal barrier.
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8. The foamable composition of declare 1, whereby the surface-active agent is current at about zero.3% to about 6.25% by weight of the provider. By time she could be AVD-5 and one article in Wikipedia (a listing ‘ships) presently links to her that approach. The pharmaceutical service according to the present invention may also be used to prepare cosmetics for beauty objective by adding into skincare agents and perfume.
conclusion
For the purpose of the present software, the term alcohol free†refers to compositions that contain no more than 7.5% by weight of any aliphatic alcohol, having one to six carbon atoms in their carbon spine, or not more than 7.5% by weight of any combination of such aliphatic alcohols.